HIGH-THROUGHPUT SERVER

FOR PROTEIN STRUCTURE PREDICTION


FREE FOR ACADEMIC RESEARCH

How FALCON@HOME Will Benefit You

Thanks thousands of volunteers for donating computation power!
HIGH-THROUGHPUT

With computation power donated from over 20,000 volunteer CPUs, FALCON@home shows a throughput as high as processing of over 1,000 proteins per day.

Accurate

FALCON@home aligns query proteins with conserved regions only rather than the full-length template directly. This helps avoid the vague alignments rooted in highly-variable regions, thus improving remote homologue identification.

EASY-TO-USE

FALCON@home is easy to use. The identified homology templates are sorted according to the alignment quality, and the predicted structures are intuitively visualized using JMOL.

OUR SOFTWARE FEATURES
 

Accurate remote homologue identificaiton

Processing over 1,000 proteins per day

Suitful to proteome-wide structure prediction

feature img

More on FALCON@home

The design of FALCON@home is based on the observation that a structural template, especially for remote homologous proteins, consists of conserved regions interweaved with highly-variable regions. The highly-variable regions lead to vague alignments in threading approaches.

FALCON@home first extracts conserved regions from each template and then aligns a query proteins with conserved regions only rather than the full-length template directly.

This helps avoid the vague alignments rooted in highly-variable regions, improving remote homologue identification.

NEWS
 

Contact Us

Bioinformatics Lab, Institute of Computing Technology
Chinese Academy of Sciences

6, Kexueyuan South Road, Zhongguancun
Beijing, China

(86)10-62600817

FALCON@ict.ac.cn